Clinical Trials

Pharmaxis conducts its own clinical trials as part of the regulatory approvals process for Aridol™ and Bronchitol™. We also support independent trials of our products to provide further evidence of the efficacy and safety of our products. Studies are being conducted by leading clinicians around the world, including Australia, New Zealand, UK, US, Canada and Switzerland.

If you would like to participate in a clinical trial being run by Pharmaxis, please contact us [link to Contact Us in the About Us section].

Aridol

Indication	Phase	Sponsor	Description	Sites	Patients	Status	Related Media and Scientific Publications
Asthma	III A301	Pharmaxis	Registration trial	Australia	646	Complete	26Oct04 01Oct04 30Jul04
Asthma	III	Investigator	Aridol as a guide for asthma management in general practice	UK	300	In progress	12Aug04

Asthma	III A305	Pharmaxis	Pre-registration trial for US FDA	USA	501	Completed	16Nov06 28Aug06 14Dec05 23Dec04
COPD	II	Investigator		Australia	40	In progress
COPD	II COPD201	Pharmaxis	Ability of Aridol to predict ICS* response	Australia	140	Completed	11apr06 15sep05
COPD	II	Investigator	Ability of Aridol to predict ICS* response * ICS = Inhaled CorticoSteroids	Switzerland		In progress	11Apr06 21Apr04 Pulm Pharmacol and Therapeutics 2005
COPD	II	Investigator	Response to ICS in patients with a positive Aridol test	Switzerland		In progress	15May07

Bronchitol

Indication	Phase	Sponsor	Description	Sites	Patients	Status	Related Media and Scientific Publications
Bronchiectasis	II B201	Pharmaxis	Proof of concept	Australia NZ	60	Complete	12May05 27Sep04 16Jul04 23Feb04
Bronchiectasis	III B301	Pharmaxis	Pre-registration trial	UK Australia New Zealand	360	Complete	29Aug07 05Jul07 02Feb07 19apr06

Cystic Fibrosis	II CF201	Pharmaxis	Proof of concept — ability to improve FEV1 and quality of life	Australia NZ	40	Complete	31Aug05 29Apr05
Cystic Fibrosis	II CF202	Pharmaxis	Dosing study	Canada Argentina	42	In progress	28Nov05 21Jul05
Cystic Fibrosis	II CF203	Pharmaxis	Comparison with Pulmozyme^®/dornase alfa	UK	42	In progress	16Dec05 09Feb05
Cystic Fibrosis	III CF301	Pharmaxis	Long term administration of Bronchitol	UK, IRE, IT Australia	250	In progress	11Apr07 06Oct06
Cystic Fibrosis	III CF302	Pharmaxis	Long term administration of Bronchitol	USA	TBA	In progress	08Nov07

Please contact Pharmaxis [link to Contact Us in About Us section] for further details about the progress of clinical trials.

Page last updated: 28 November 2007