News
For the latest media releases and news about Pharmaxis Ltd, please select from the following articles. Material news announcements made by Pharmaxis are first filed with the Australian Securities Exchange (ASX) and are also available on the ASX website.
Pharmaxis Appoints Dr Neil Graham as Director
Pharmaceutical research company Pharmaxis Ltd (ASX: PXS) is pleased to announce the appointment of experienced senior global pharma and biotech executive Dr Neil Graham to the Board as a non-executive director.
Dr Graham is a medicines development expert and infectious diseases epidemiologist who has had a distinguished academic and business career. He recently retired as Vice President of Strategic Program Direction at Regeneron (REGN:US) where he was responsible for the pipeline portfolio and successfully leading development of immunology and inflammation products from preclinical development to post-launch.
Read full media release - pdfPharmaxis CEO to Present at Virtual Health Conference
Pharmaxis Ltd (ASX: PXS) chief executive officer Mr Gary Phillips will present at the NWR Virtual Health Conference to be held on Friday 1 May & Monday 4 May, 2020. Mr Phillips will provide details of recent progress in the Pharmaxis drug discovery pipeline and additional commentary on the information included in the latest Pharmaxis Quarterly Shareholder Update released earlier today, available of the company website.
Shareholders and investors are invited to participate in this free event.
Event: NWR Communications Virtual Health Conference
Presenting: Gary Phillips, CEO
Time/date: 1:40pm AEST, Friday 1 May
The event is free and investors should register in advance to view the presentation at: https://t.co/sY5jB3KKEi?amp=1
Read full media release - pdfPharmaxis Cancer Drug Ready to Commence Myelofibrosis Phase 2 Studies Q4 2020
Pharmaceutical research company Pharmaxis Ltd (ASX: PXS) today announced that following positive results from phase 1b and long term toxicity studies, the company is now progressing to a phase 2 study of its oral anti-fibrotic pan-Lysyl Oxidase (LOX) inhibitor PXS-5505 for treatment of the rare bone cancer, myelofibrosis (MF).
- Multiple ascending dose stage of Phase 1 trial demonstrates a well-tolerated drug that effectively inhibits all enzymes in the lysyl oxidase family that are involved in fibrosis.
- Long term toxicity studies completed clearing the way for 6-month phase 2 studies in several cancers with opportunity to demonstrate disease modifying efficacy.
- Pre-clinical program, regulatory advice and opinion from leading clinicians supports progression into phase 2 study of myelofibrosis, a rare bone cancer with high unmet need and significant market opportunity.
- Pharmaxis advances its clinical stage pipeline in fibrosis that includes selective LOXL2 inhibitors (PXS-5382 and PXS-5338) for chronic fibrotic diseases like NASH and IPF, the oral pan-LOX inhibitor (PXS-5505) for acute fibrosis and cancer, and a topical pan-LOX inhibitor for scarring.