Shareholders

	Ordinary Shares	ADS equivalents*
Issued Shares at 30 June 2010	225,410,234	15,027,349
Employee options at 30 June 2010	13,155,250	877,017
* One ADS (American Depositary Share) is equivalent to 15 ordinary shares

The top 20 Shareholders in Pharmaxis Ltd on 30 June 2010 are:

Name	Number	% Total
1. National Nominees Limited	40,647,014	18.0%
2. Citicorp Nominees Pty Limited	27,465,828	12.2%
3. JP Morgan Nominees Australia Limited	22,199,908	9.9%
4. HSBC Custody Nomiees (Australia) Limited	17,937,192	8.0%
5. Aust Executor Trustees NSW Ltd	9,252,112	4.1%
6. ANZ Nominees Limited	7,214,804	3.2%
7. Cogent Nominees Pty Limited	7,070,075	3.1%
8. UBS Nominees Pty Ltd	1,903,239	0.8%
9. The Australian National University	1,900,000	0.8%
10. AET Structured Finance Services Pty Limited	1,772,883	0.8%
11. Phillip Asset Management Ltd	1,599,089	0.7%
12. KFT Investments Pty Ltd	1,551,822	0.7%
13. RBC Dexia Investor Services Australia Nominees Pty Limited (BKCust a/c)	1,492,346	0.7%
14. UBS Wealth Management Australia Nominees Pty Ltd	1,082,012	0.5%
15. Dr Alan Duncan Robertson	1,045,000	0.5%
16. Citicorp Nominees Pty Limited (Cwlth Bank Off Super a/c)	1,043,034	0.5%
17. MF Custodians Ltd	800,000	0.4%
18. Capital Regional et Cooperatif Desjardins	697,430	0.3%
19. Harbour Nominees Pty Ltd	670,339	0.3%
20. CMG Equity Investments Pty Ltd	649,454	0.3%

Pharmaxis has received the following substantial shareholder notices:

Name	Percent	Date
Orbis Global Equity Fund Ltd	16.72%	22 April 2010
Arnhem Investment Management Pty Ltd (previously Fortis Investment Management Australia Limited)	9.77%	13 February 2009