News

For the latest media releases and news about Pharmaxis Ltd, please select from the following articles. Material news announcements made by Pharmaxis are first filed with the Australian Securities Exchange (ASX) and are also available on the ASX website.

13th Oct 21

Pharmaxis Doses First Patient in Phase 2 Bone Marrow Cancer Trial

Clinical stage drug development company Pharmaxis Ltd (ASX: PXS) today announced that it has commenced dosing in the phase 2 clinical trial studying its drug PXS-5505 in patients with the bone marrow cancer myelofibrosis. 

Read full media release - pdf
5th Oct 21

Pharmaxis Cleared to Progress to Phase 2 Bone Marrow Cancer Trial

Clinical stage drug development company Pharmaxis Ltd (ASX: PXS) today announced further positive results of data analysis from a phase 1c clinical trial (MF-101) studying its drug PXS-5505 in patients with the bone marrow cancer myelofibrosis for 28 days at three dosage levels.

Assessment with Pharmaxis’ proprietary assays of the highest dose has shown inhibition of the target enzymes, LOX and LOXL2, at greater than 90% over a 24-hour period at day 7 and day 28. The trial safety committee has reviewed the results and having identified no safety signals, has cleared the study to progress to the phase 2 dose expansion phase where 24 patients will be treated at the highest dose twice a day for 6 months.

Read full media release - pdf